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There are many types of throat sprays.  Generally, they can be for pain relief, hydration or anti-septic.  Pain relief throat sprays are good for pain control. Hydrating throat sprays are good for dry mouth and throat. Anti-septic throat sprays help to clean the surface of the wound.  It can help to relief mild throat infections. However, long term anti-septic sprays may alter the mouth natural flora leading to growth of other undesired organism.  As such, doctor advice is needed if long term anti-septic throat sprays are needed.