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Dr. John Hverified
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Hi Pa-Kihn
Thanks for the question. I would say there are many medications out there in the market which aims to reduce weight and in term reduces the severity of the fatty liver. You are absolutely right, reducing the amount or severity of liver fat, reduces the risk of progressing to more severe form of fatty liver like cirrhosis.

There are also several drugs in the research pipeline that aims to work on the different pathways of fatty liver to reduce the 'liver fat'. For now, I would say the most effective medications that reduces the degree of fat in the liver are those medications that works for you and can help you lose weight. 

GLP-1 agonist for example, works on the appetite pathway as well as reversing the insulin resistance (that will eventually lead to diabetes). So patients on this drug tend to have reduced appetite, reduced intake, and improvement in insulin sensitivity which reduces the amount of the fat in the liver.

If you can lose 7-10% of your body weight, you have a very good chance at reducing the amount of fat in the liver. I always tell my patients lifestyle modification is more important than medications alone, because you carry the lifestyle changes with you for the rest of your life!!